Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.57 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.57 |
| ▸ | ADRA1A known ✓ | P35348 | 7/20 | 0.48 |
| ▸ | ADRA1D known ✓ | P25100 | 6/20 | 0.48 |
| ▸ | ADRA1B known ✓ | P35368 | 6/20 | 0.48 |
| ▸ | ADRA2C known ✓ | P18825 | 6/20 | 0.48 |
| ▸ | ADRA2A known ✓ | P08913 | 4/20 | 0.48 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.48 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7141352 | 1.00 | NISCH (0.57) | NISCHMAOAMAOBHTR1DTAAR1 | |
| SCHEMBL7518582 | 0.92 | NISCH (0.67) | NISCHMAOAMAOBHTR1DTAAR1 | |
| SCHEMBL7141177 | 0.82 | ADRA1A (0.47) | NISCHMAOAMAOBHTR1DTAAR1 | |
| SCHEMBL7141308 | 0.82 | ADRA1A (0.47) | NISCHMAOAMAOBHTR1DTAAR1 | |
| SCHEMBL7141180 | 0.82 | ADRA1A (0.47) | NISCHMAOAMAOBHTR1DTAAR1 | |
| SCHEMBL9575326 | 0.81 | NISCH (0.80) | NISCHMAOAMAOBHTR1DTAAR1 | |
| Sulfuric Acid SCHEMBL18298127 | 0.81 | MEN1 (0.59) | ADRA2CADRA2ALMNAADRA2BKCNH2 | |
| Sulfuric Acid SCHEMBL10624570 | 0.81 | MEN1 (0.59) | ADRA2CADRA2ALMNAADRA2BKCNH2 | |
| Sulfuric Acid SCHEMBL38021 | 0.81 | MEN1 (0.59) | ADRA2CADRA2ALMNAADRA2BKCNH2 | |
| Sulfuric Acid SCHEMBL491381 | 0.81 | MEN1 (0.59) | ADRA2CADRA2ALMNAADRA2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521683-B1 | Antistatic agents and resin compositions incorporated therein | WITCO CORPORATION | 2003-02-18 | — | — | US | disclosed |
| EP-1177254-A1 | ANTISTATIC AGENTS AND RESIN COMPOSITIONS INCORPORATED THEREIN | Crompton Corporation (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064970-A1 | ANTISTATIC AGENTS AND RESIN COMPOSITIONS INCORPORATED THEREIN | CROMPTON CORPORATION (US) | 2000-11-02 | — | — | WO | disclosed |