Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312771 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2CA14ALDH1A1CA12CA1 | |
| SCHEMBL26316150 | 0.80 | ALDH1A1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL26316135 | 0.80 | ALDH1A1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13898920 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2CA14ALDH1A1CA12CA1 | |
| SCHEMBL26316235 | 0.77 | APLNR (0.35) | CA14ALDH1A1CA12TDP1CA1 | |
| SCHEMBL26316257 | 0.77 | APLNR (0.35) | CA14ALDH1A1CA12TDP1CA1 | |
| SCHEMBL7159806 | 0.76 | TDP1 (0.36) | GAAALDH1A1TDP1 | |
| SCHEMBL926431 | 0.76 | — | — | |
| SCHEMBL29016960 | 0.76 | TDP1 (0.36) | GAAALDH1A1TDP1 | |
| SCHEMBL29016903 | 0.76 | TDP1 (0.36) | GAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278747-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | Abbott Laboratories (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001083484-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |