Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30715562 | 0.81 | SIGMAR1 (0.39) | SIGMAR1PLAUIDO1PDPK1MTNR1A | |
| SCHEMBL7783911 | 0.81 | SIGMAR1 (0.39) | SIGMAR1PLAUMTNR1AMTNR1BANPEP | |
| SCHEMBL6666465 | 0.81 | SIGMAR1 (0.39) | SIGMAR1PLAUIDO1PDPK1MTNR1A | |
| SCHEMBL8765441 | 0.75 | SIGMAR1 (0.35) | SIGMAR1PDPK1 | |
| SCHEMBL6721448 | 0.72 | SIGMAR1 (0.43) | SIGMAR1PLAUIDO1PDPK1MTNR1A | |
| SCHEMBL16340795 | 0.71 | TSHR (0.35) | SIGMAR1IDO1 | |
| SCHEMBL10780065 | 0.71 | SIGMAR1 (0.42) | SIGMAR1PLAUIDO1PDPK1MTNR1A | |
| SCHEMBL6676676 | 0.71 | PLAU (0.45) | SIGMAR1PLAUIDO1PDPK1ANPEP | |
| SCHEMBL5255259 | 0.71 | PLAU (0.45) | SIGMAR1PLAUIDO1PDPK1ANPEP | |
| SCHEMBL30724832 | 0.71 | SIGMAR1 (0.42) | SIGMAR1PLAUIDO1PDPK1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6110960-A | FOR TREATING ARTHRITIS AND AS ANALGESIC | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |