Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146457 | 0.93 | CHRM1 (0.43) | MCHR1RAB9ASMN1; SMN2CHRM1CCR3 | |
| SCHEMBL7148150 | 0.88 | CHRM1 (0.46) | MCHR1CHRM1USP2POLBALDH1A1 | |
| SCHEMBL7143055 | 0.85 | DRD4 (0.47) | MCHR1RAB9ASMN1; SMN2CHRM1TP53 | |
| SCHEMBL7146510 | 0.85 | SENP5 (0.42) | MCHR1RAB9ASMN1; SMN2CCR3NPC1 | |
| SCHEMBL3479854 | 0.84 | KMT2A (0.53) | MCHR1RAB9ASMN1; SMN2CCR3NPC1 | |
| SCHEMBL7145105 | 0.83 | CHRM1 (0.44) | MCHR1RAB9ACHRM1CCR3USP2 | |
| SCHEMBL7143115 | 0.83 | MEN1 (0.43) | RAB9ACHRM1NPC1USP2POLB | |
| SCHEMBL7144671 | 0.83 | MEN1 (0.44) | MCHR1CHRM1USP2POLBALDH1A1 | |
| SCHEMBL7148318 | 0.82 | CHRM1 (0.43) | MCHR1RAB9ACHRM1CCR3USP2 | |
| SCHEMBL7146507 | 0.82 | CYP2C9 (0.47) | MCHR1CHRM1CCR3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |