Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146510 | 0.89 | SENP5 (0.42) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL7146066 | 0.88 | MCHR1 (0.45) | MAPTMEN1KMT2ASMN1; SMN2MCHR1 | |
| SCHEMBL7146835 | 0.88 | SMN1; SMN2 (0.48) | MAPTCYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7148150 | 0.87 | CHRM1 (0.46) | MCHR1MMP13CHRM1 | |
| SCHEMBL7147874 | 0.87 | CCR2 (0.44) | MMP13CHRM1 | |
| SCHEMBL7146457 | 0.86 | CHRM1 (0.43) | DRD4SMN1; SMN2MCHR1RAB9AMMP13 | |
| SCHEMBL7145387 | 0.86 | LMNA (0.45) | DRD4DRD2MMP13CHRM1 | |
| SCHEMBL7139305 | 0.86 | MAPK14 (0.43) | CYP3A4MEN1KMT2ASMN1; SMN2CXCR3 | |
| SCHEMBL7144671 | 0.85 | MEN1 (0.44) | MEN1KMT2AMCHR1MMP13CHRM1 | |
| SCHEMBL7141820 | 0.85 | MCHR1 (0.43) | DRD4MEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |