Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834026 | 0.88 | RAB9A (0.61) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL17834016 | 0.83 | RAB9A (0.48) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL29353662 | 0.83 | NPC1 (0.67) | RAB9AL3MBTL1NPC1SMN1; SMN2THRB | |
| SCHEMBL4413466 | 0.82 | RAB9A (1.00) | RAB9AL3MBTL1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL15543138 | 0.81 | HSP90AA1 (0.51) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL7140847 | 0.80 | LMNA (0.59) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8223284 | 0.80 | RAB9A (0.57) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL15551853 | 0.79 | RAB9A (0.45) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL15542738 | 0.79 | RAB9A (0.45) | RAB9AL3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL10980707 | 0.79 | MEN1 (0.67) | RAB9AL3MBTL1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127487-C | Phthalazinones | ALTANA PHARMA AG (DE) | 2003-11-12 | — | — | CN | disclosed |
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |