Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978436 | 0.85 | KMT2A (0.50) | LMNASMN1; SMN2KMT2AMEN1APOBEC3G | |
| SCHEMBL17978445 | 0.84 | MEN1 (0.49) | LMNASMN1; SMN2KMT2AMEN1XDH | |
| SCHEMBL1674287 | 0.81 | XDH (0.49) | SMN1; SMN2KMT2AMEN1XDHALDH1A1 | |
| SCHEMBL10980707 | 0.81 | MEN1 (0.67) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7142227 | 0.80 | RAB9A (0.68) | SMN1; SMN2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL10734423 | 0.79 | MEN1 (0.49) | LMNASMN1; SMN2KMT2AMEN1XDH | |
| SCHEMBL4825891 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AAPOBEC3GALDH1A1 | |
| SCHEMBL3544012 | 0.76 | LMNA (0.71) | LMNASMN1; SMN2KMT2AMEN1AOC3 | |
| SCHEMBL9660058 | 0.76 | ABCG2 (0.51) | SMN1; SMN2KMT2AMEN1XDH | |
| Hydrochloric Acid SCHEMBL9098315 | 0.75 | ABCG2 (0.50) | SMN1; SMN2KMT2AMEN1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127487-C | Phthalazinones | ALTANA PHARMA AG (DE) | 2003-11-12 | — | — | CN | disclosed |
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-6103718-A | Phthalazinones | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-15 | — | — | US | disclosed |
| CN-1249749-A | Phthalazinones | BYK GULDEN LOMBERC CHEM FAB GM (DE) | 2000-04-05 | — | — | CN | disclosed |
| EP-0971901-A1 | PHTHALAZINONES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998031674-A1 | PHTHALAZINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-23 | — | — | WO | disclosed |