Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TACR3 | P29371 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446588 | 0.87 | LSS (0.55) | LSSKCNH2MGLLNPY2RGAA | |
| SCHEMBL7141682 | 0.85 | MGLL (0.44) | LSSMGLL | |
| SCHEMBL7145847 | 0.84 | LSS (0.45) | LSSMGLLNPY2RGAA | |
| SCHEMBL6449787 | 0.83 | LSS (0.62) | LSSNPY2RGAA | |
| SCHEMBL7202905 | 0.82 | LSS (0.69) | LSSKCNH2 | |
| SCHEMBL6450155 | 0.81 | LSS (0.68) | LSSNPY2R | |
| SCHEMBL6449244 | 0.80 | LSS (0.52) | LSSNPY2RGAA | |
| SCHEMBL6448141 | 0.80 | LSS (0.52) | LSSMGLLNPY2RGAA | |
| SCHEMBL6450779 | 0.80 | LSS (0.61) | LSSMGLLNPY2RGAA | |
| SCHEMBL6446450 | 0.80 | LSS (0.56) | LSSNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317432-A1 | PIPERIDINE DERIVATIVES FOR USE AS 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020483-A1 | PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-14 | — | — | WO | disclosed |