Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990727 | 0.90 | CYP17A1 (0.56) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL756686 | 0.87 | CYP17A1 (0.46) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL2786810 | 0.86 | RARB (0.55) | CYP17A1CYP21A2CYP11B1MAPTLPL | |
| SCHEMBL3153225 | 0.86 | CYP17A1 (0.45) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL19400460 | 0.85 | RARB (0.57) | CYP17A1CYP21A2CYP11B1RAB9AMAPT | |
| SCHEMBL7552100 | 0.85 | MAOB (0.59) | TAAR1MCL1MAOBNPC1RAB9A | |
| SCHEMBL502975 | 0.84 | TAAR1 (0.45) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL3162709 | 0.83 | HRH3 (0.43) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL13033564 | 0.83 | CYP17A1 (0.40) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 | |
| SCHEMBL8990730 | 0.83 | MAOB (0.57) | CYP17A1CYP21A2CYP11B1TAAR1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279565-A2 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-4279565-A2 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3763802-B1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| CN-110790641-B | Method for producing compound having oxydifluoromethylene skeleton | 大金工业株式会社 | 2023-02-28 | — | — | CN | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| EP-3763802-A1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-3455328-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2020-03-04 | — | — | EP | disclosed |
| CN-110713837-A | Thiophene compound, liquid crystal medium and liquid crystal display comprising same | 默克专利股份有限公司 | 2020-01-21 | — | — | CN | disclosed |
| WO-2017194665-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | WO | disclosed |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6605747-B2 | Reacting the starting material, an alpha , alpha -difluorocyclohexylidene derivative with a halogen to produce an intermediate, reacting the intermediate with a phenol compound in presence of a base | CHISSO CORPORATION (JP) | 2003-08-12 | — | — | US | disclosed |
| US-6579577-B2 | High voltage holding ratio which has a very small degree of temperature dependence, a low threshold voltage | CHISSO CORPORATION (JP) | 2003-06-17 | — | — | US | disclosed |
| US-20020166994-A1 | Substituted benzene derivative, liquid crystal composition, and liquid crystal display element | CHISSO CORPORATION (JP) | 2002-11-14 | — | — | US | disclosed |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1182186-A2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-6344247-B1 | HIGH VOLTAGE HOLDING RATIO AND A LOW THRESHOLD VOLTAGE, LITTLE VARIATION OF THESE PROPERTIES DEPENDING ON TEMPERATURE CHANGE, COMPATIBILITY WITH OTHER LIQUID CRYSTAL MATERIALS | CHISSO CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-0989107-A1 | TERPHENYL DERIVATIVE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-03-29 | — | — | EP | disclosed |
| EP-0934919-A1 | SUBSTITUTED BENZENE DERIVATIVE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, PYM1, SCFD1 | CYP17A1 800/4885CYP21A2 806/4885CYP11B1 2724/4885 |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, SCFD1, AFF1 | CYP17A1 779/4885CYP21A2 818/4885CYP11B1 2710/4885 |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | LEF1, AFF1, RCC1 | CYP17A1 856/4885CYP21A2 729/4885CYP11B1 3128/4885 |
| US-20020166994-A1 | Substituted benzene derivative, liquid crystal composition, and liquid crystal display element | OCIAD2, OCIAD1, POU2F1 | CYP17A1 1069/4885CYP21A2 739/4885CYP11B1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.