Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714257 | 0.87 | CYP17A1 (0.53) | CYP17A1CYP21A2CYP11B1CNR2MAOB | |
| SCHEMBL8547681 | 0.87 | CNR2 (0.54) | CNR2MAOBTAAR1CHKAMCL1 | |
| SCHEMBL13033575 | 0.87 | MAOB (0.40) | CYP17A1CYP21A2CYP11B1CNR2MME | |
| SCHEMBL21020527 | 0.86 | CHKA (0.46) | CYP17A1CYP21A2CYP11B1CNR2MME | |
| SCHEMBL13033564 | 0.82 | CYP17A1 (0.40) | CYP17A1CYP21A2CYP11B1CNR2MME | |
| SCHEMBL14525747 | 0.79 | RARB (0.44) | CYP17A1CYP21A2CYP11B1CNR2MAOB | |
| SCHEMBL8990727 | 0.78 | CYP17A1 (0.56) | CYP17A1CYP21A2CYP11B1CNR2MAOB | |
| SCHEMBL13349208 | 0.77 | DAO (0.39) | CYP17A1CYP21A2CYP11B1CNR2NPC1 | |
| SCHEMBL7552100 | 0.77 | MAOB (0.59) | MAOBTAAR1MCL1NPC1RAB9A | |
| SCHEMBL7451380 | 0.77 | MAOB (0.59) | MAOBTAAR1MCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586803-B2 | Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-8586153-B2 | Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-8586153-B2 | Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-8586803-B2 | Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device | JNC CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130088658-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-11 | — | — | US | disclosed |
| US-20130088658-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-11 | — | — | US | disclosed |
| US-20130088658-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-11 | — | — | US | disclosed |
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | HASEBA YASUHIRO (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20100296029-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL DEVICE | CHISSO CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100296029-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL DEVICE | CHISSO CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7722783-B2 | Optically isotropic liquid crystal medium and optical device | CHISSO CORPORATION (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7722783-B2 | Optically isotropic liquid crystal medium and optical device | CHISSO CORPORATION (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7722783-B2 | Optically isotropic liquid crystal medium and optical device | CHISSO CORPORATION (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-2098583-A2 | Optically isotropic liquid crystal medium and optical device | Chisso Corporation (JP) | 2009-09-09 | — | — | EP | disclosed |
| EP-2098583-A2 | Optically isotropic liquid crystal medium and optical device | Chisso Corporation (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090135368-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | CHISSO CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090135368-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | CHISSO CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090135368-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | CHISSO CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085306-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE | DDT, BRAF, CFAP410 | CYP17A1 1536/4885CYP21A2 1514/4885CYP11B1 1677/4885 |
| US-20100296029-A1 | CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL DEVICE | DDT, BRAF, LEF1 | CYP17A1 1551/4885CYP21A2 1326/4885CYP11B1 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.