Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605268 | 0.83 | PTGS2 (0.51) | AKR1C3PTGS2 | |
| SCHEMBL8667916 | 0.82 | ALDH1A1 (0.48) | TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL7142643 | 0.78 | GFER (0.58) | GAACA1CA2CA9CA12 | |
| SCHEMBL55092 | 0.78 | TSHR (0.62) | GAACA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL560710 | 0.75 | GAA (0.60) | GAACA1CA2CA9CA12 | |
| SCHEMBL27730326 | 0.74 | ENPP2 (0.45) | AKR1C3CA2CYP3A4CYP2C9PTGS2 | |
| SCHEMBL1428902 | 0.74 | ENPP2 (0.48) | AKR1C3PTGS2ENPP2 | |
| SCHEMBL7524100 | 0.74 | ENPP2 (0.48) | AKR1C3PTGS2ALDH1A1CYP1A2ENPP2 | |
| SCHEMBL5852576 | 0.72 | MAOB (0.52) | GAATSHRCYP3A4CYP2C9TDP1 | |
| SCHEMBL8366101 | 0.72 | MAOB (0.52) | GAATSHRCYP3A4CYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189929-B1 | FACTOR VIIA INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |