Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141483 | 0.84 | SETD7 (0.42) | HRH1SETD7CHRM2HTR1ACHRM1 | |
| SCHEMBL7136207 | 0.83 | SETD7 (0.59) | HRH1SETD7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8200919 | 0.82 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7135254 | 0.80 | SIGMAR1 (0.45) | ADRA1AKCNH2SIGMAR1TDP1 | |
| SCHEMBL7136762 | 0.80 | HRH1 (0.64) | HRH1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Oxalic Acid SCHEMBL7138914 | 0.79 | KDM4E (0.40) | HRH1SETD7CYP2D6CYP2C19CHRM2 | |
| SCHEMBL7142235 | 0.78 | HRH1 (0.41) | HRH1SETD7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7136916 | 0.78 | SETD7 (0.38) | HRH1SETD7CHRM2HTR1ACHRM1 | |
| Oxalic Acid SCHEMBL7138856 | 0.78 | HTR5A (0.49) | HRH1HTR1ADRD2HTR2AHTR2B | |
| SCHEMBL7139800 | 0.76 | PRMT5 (0.36) | HRH1SETD7CHRM2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675887-B1 | ANTIALLERGIC TRIAZOLOBENZAZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-02 | — | — | EP | disclosed |