Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6279797 | 0.99 | TDP1 (0.46) | TDP1KMT2ARAB9ANPC1CSF1R | |
| SCHEMBL7148265 | 0.89 | NPC1 (0.51) | TDP1KMT2ARAB9ANPC1CSF1R | |
| Bromide SCHEMBL6284648 | 0.87 | NPC1 (0.50) | TDP1KMT2ARAB9ANPC1CSF1R | |
| SCHEMBL7142799 | 0.87 | NAMPT (0.49) | KMT2ARAB9ANPC1GAAALDH1A1 | |
| Bromide SCHEMBL6276160 | 0.85 | NAMPT (0.48) | KMT2ARAB9ANPC1GAAALDH1A1 | |
| SCHEMBL7148793 | 0.81 | GAA (0.45) | TDP1KMT2ARAB9ANPC1GAA | |
| SCHEMBL7140967 | 0.81 | SMN1; SMN2 (0.51) | TDP1GAAALDH1A1KCNA5TBXAS1 | |
| Bromide SCHEMBL6276618 | 0.80 | GAA (0.44) | TDP1KMT2ARAB9ANPC1GAA | |
| Bromide SCHEMBL6282444 | 0.80 | SMN1; SMN2 (0.50) | TDP1GAAALDH1A1KCNA5TBXAS1 | |
| SCHEMBL7146375 | 0.80 | CYP1A2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |