Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144492 | 0.79 | MEN1 (0.39) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| SCHEMBL22032844 | 0.78 | SIGMAR1 (0.48) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| Hydrochloric Acid SCHEMBL18167506 | 0.77 | SIGMAR1 (0.47) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| SCHEMBL7144413 | 0.76 | SIGMAR1 (0.39) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| SCHEMBL7136147 | 0.76 | MEN1 (0.37) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7517078 | 0.75 | SIGMAR1 (0.38) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7511006 | 0.75 | MEN1 (0.36) | MEN1KMT2ATSHRL3MBTL1CYP2D6 | |
| SCHEMBL2638266 | 0.74 | P2RX7 (0.34) | L3MBTL1 | |
| SCHEMBL7143023 | 0.74 | P2RX7 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7517660 | 0.71 | L3MBTL1 (0.45) | MEN1KMT2ATSHRL3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | claimed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | claimed |
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |