Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334104 | 0.76 | TSHR (0.47) | HCRTR1GAAKDM4EL3MBTL1GLA | |
| SCHEMBL17977307 | 0.75 | MKNK1 (0.44) | HCRTR1KDM4EL3MBTL1GLAKMT2A | |
| SCHEMBL1205875 | 0.74 | TDP1 (0.51) | HCRTR1GAAKDM4EL3MBTL1GLA | |
| SCHEMBL5178794 | 0.71 | TSHR (0.49) | GAAKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4318856 | 0.68 | TSHR (0.47) | HCRTR1GAAKDM4EL3MBTL1GLA | |
| SCHEMBL5460045 | 0.65 | L3MBTL1 (0.65) | KDM4EL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL4284044 | 0.65 | KMT2A (0.50) | HCRTR1GAAKDM4EL3MBTL1GLA | |
| SCHEMBL127280 | 0.64 | ALDH1A1 (0.39) | GAAKDM4EL3MBTL1CYP2C19GLA | |
| SCHEMBL4998751 | 0.64 | KDM4E (0.41) | GAAKDM4EL3MBTL1GLAKMT2A | |
| SCHEMBL9024146 | 0.63 | L3MBTL1 (0.45) | KDM4EL3MBTL1GLAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289939-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | claimed |
| WO-2001090051-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | claimed |
| EP-1289939-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090051-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |