SCHEMBL7143473

SCHEMBL7143473

CN(C)C(=O)Nc1ccc(F)c([Ti])c1F

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.57
TSHR P16473 1/20 0.42
ALPL P05186 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
TP53 P04637 1/20 0.39
ALOX12 P18054 1/20 0.39
ALDH1A1 P00352 1/20 0.37
KDM4E B2RXH2 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7137151 0.81 HDAC1 (0.46) ALDH1A1KDM4ESMN1; SMN2
SCHEMBL27508225 0.77 L3MBTL1 (0.44) HTTALOX12ALDH1A1KDM4EKMT2A
SCHEMBL6850023 0.75 ALDH1A1 (0.38) HTTTP53ALDH1A1
SCHEMBL7144364 0.74 MAPK1 (0.47) HTTALPLALPIALPGTP53
SCHEMBL27515374 0.73 POLB (0.56) HTTALDH1A1KMT2ASMN1; SMN2
SCHEMBL27468722 0.72 HDAC1 (0.55) HTTTP53KMT2ASMN1; SMN2
SCHEMBL7580934 0.72 CETP (0.48) TSHRALDH1A1KDM4E
SCHEMBL7580924 0.72 KDM4E (0.47) ALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL23169175 0.72 HTT (0.64) HTTALPLALPIALPGALDH1A1
SCHEMBL2767050 0.71 HTT (0.73) HTTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed