Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146217 | 0.91 | PTGS2 (0.44) | PTGS2PTGS1P2RY6TMEM97CA12 | |
| SCHEMBL7147341 | 0.89 | P2RY6 (0.44) | PTGS2PTGS1P2RY6TMEM97ADRA2A | |
| SCHEMBL7144214 | 0.89 | PTGS2 (0.54) | PTGS2PTGS1P2RY6DRD5 | |
| SCHEMBL7142450 | 0.81 | PTGS2 (0.40) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7149865 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL6093866 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7146315 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1P2RY6DRD5 | |
| SCHEMBL7146353 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1P2RY6TMEM97ADRA2A | |
| SCHEMBL6095135 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7148451 | 0.81 | P2RY6 (0.54) | PTGS2PTGS1P2RY6TMEM97ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |