Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146217 | 0.85 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL6092400 | 0.83 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL6092160 | 0.83 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7143493 | 0.81 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL7149821 | 0.81 | PTGS2 (0.45) | PTGS2PTGS1HDAC3HDAC1HDAC2 | |
| SCHEMBL7144214 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7147341 | 0.81 | P2RY6 (0.44) | PTGS2PTGS1 | |
| SCHEMBL7146745 | 0.78 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7148451 | 0.77 | P2RY6 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7146353 | 0.77 | PTGS2 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |