Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546561 | 1.00 | LMNA (0.64) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL6397082 | 0.90 | LMNA (0.69) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL30704400 | 0.88 | LMNA (0.68) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL11037269 | 0.87 | LMNA (0.66) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL11039673 | 0.87 | LMNA (0.66) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL30947438 | 0.85 | LMNA (0.78) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL27031062 | 0.84 | POLB (0.58) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL763166 | 0.82 | LMNA (0.64) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL2149052 | 0.82 | LMNA (0.64) | LMNAHPGDHTTALDH1A1MAPT | |
| SCHEMBL961132 | 0.82 | LMNA (0.64) | LMNAHPGDHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514824-A | Tri-ring compound, preparation method and application thereof | 上海科技大学 | 2023-08-01 | — | — | CN | disclosed |
| EP-0808313-B1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-13 | — | — | EP | disclosed |
| US-5919788-A | PSYCHOLOGICAL DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1999-07-06 | — | — | US | disclosed |
| EP-0822814-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0822814-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5668148-A | BENIGN PROSTATIC HYPERTROPHY | MERCK & CO., INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996032938-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| US-4680296-A | ANTIALLERGENS, ANTIPRUITIC AGENTS | SYNTHELABO (FR) | 1987-07-14 | — | — | US | disclosed |