Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037269 | 1.00 | LMNA (0.66) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL30704400 | 0.98 | LMNA (0.68) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL6397082 | 0.94 | LMNA (0.69) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL30546561 | 0.87 | LMNA (0.64) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL7143500 | 0.87 | LMNA (0.64) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL30947438 | 0.87 | LMNA (0.78) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL25315525 | 0.84 | RAB9A (0.68) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL5500024 | 0.84 | LMNA (0.66) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL11139092 | 0.84 | RAB9A (0.68) | LMNAHPGDALDH1A1MAPTTSHR | |
| SCHEMBL8134198 | 0.84 | LMNA (0.66) | LMNAHPGDALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199555-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | Université d'Orléans (FR) | 2024-06-20 | — | — | US | disclosed |
| EP-4308119-A1 | <SUP2/>? <SUB2/>?7?APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HTRECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | Centre National de la Recherche Scientifique (FR) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022195102-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-09-22 | — | — | WO | disclosed |
| EP-0058975-B1 | SUBSTITUTED N-(4-INDOLYL-PIPERIDINO-ALKYL) BENZIMIDAZOLONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4359468-A | ALSO USEFUL AS HYPOTENSIVE AGE NTS | BOEHRINGER INGELHEIM LTD. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0058975-A1 | Substituted N-(4-indolyl-piperidino-alkyl) benzimidazolones, processes for their preparation and their use as pharmaceutical preparations | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1982-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199555-A1 | APPLICATIONS OF BIASED LIGANDS OF THE SEROTONIN 5-HT7 RECEPTOR FOR THE TREATMENT OF PAIN, MULTIPLE SCLEROSIS AND THE CONTROL OF THERMOREGULATION | HTR7, HTR1A, CNR1 | LMNA 3768/4885HPGD 3541/4885ALDH1A1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.