Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7517083 | 0.99 | CHRM2 (0.34) | CHRM2CHRM1CHRM3KDM1AMAOA | |
| SCHEMBL7146409 | 0.75 | PAX8 (0.35) | CHRM2CHRM1CHRM3KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL7513708 | 0.74 | PAX8 (0.35) | CHRM2CHRM1CHRM3KDM1AMAOA | |
| SCHEMBL5599227 | 0.73 | GABRP (0.46) | — | |
| Hydrochloric Acid SCHEMBL7517080 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL5599953 | 0.71 | GABRP (0.48) | — | |
| Hydrochloric Acid SCHEMBL7512392 | 0.70 | NPC1 (0.34) | KDM1AMAOAMAOBBCHE | |
| Hydrochloric Acid SCHEMBL7512582 | 0.70 | OPRL1 (0.35) | CHRM2CHRM1CHRM3KDM1AMAOA | |
| SCHEMBL7144483 | 0.69 | CHRM2 (0.33) | CHRM2CHRM1CHRM3KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL7517092 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |