Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.62 |
| ▸ | MMP9 | P14780 | 9/20 | 0.52 |
| ▸ | MMP2 | P08253 | 8/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149068 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| Acetic Acid SCHEMBL7153863 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| Hydrochloric Acid SCHEMBL6622253 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| SCHEMBL6620316 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BMMP9MMP2ITGAV | |
| Hydrochloric Acid SCHEMBL6622243 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| SCHEMBL6620319 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BMMP9MMP2ITGAV | |
| Hydrochloric Acid SCHEMBL6622249 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| Hydrochloric Acid SCHEMBL6633329 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| SCHEMBL7147856 | 0.82 | MMP2 (0.58) | ITGB3ITGA2BMMP9MMP2MMP8 | |
| SCHEMBL7357056 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BMMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528534-B2 | Useful as glycoprotein IIb/IIIa antagonists for prophylaxis thrombosis, therapy of atheroschlerosis, arterioschlerosis, acute myocardial infarction, chronic stable angina, unstable angina, transient ischemic attacks and strokes | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-04 | — | — | US | disclosed |