Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144472 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| SCHEMBL6620445 | 0.87 | CYP2D6 (0.50) | ITGB3ITGA2BCYP2D6CHRM2CHRM3 | |
| SCHEMBL6620443 | 0.87 | CYP2D6 (0.50) | ITGB3ITGA2BCYP2D6CHRM2CHRM3 | |
| SCHEMBL7147856 | 0.84 | MMP2 (0.58) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| Acetic Acid SCHEMBL7153863 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| SCHEMBL7357056 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| Hydrochloric Acid SCHEMBL6622253 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BITGAVSMN1; SMN2MMP9 | |
| Hydrochloric Acid SCHEMBL6622243 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| Hydrochloric Acid SCHEMBL6633329 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BITGAVMMP9MMP8 | |
| Hydrochloric Acid SCHEMBL6622249 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2BITGAVSMN1; SMN2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528534-B2 | Useful as glycoprotein IIb/IIIa antagonists for prophylaxis thrombosis, therapy of atheroschlerosis, arterioschlerosis, acute myocardial infarction, chronic stable angina, unstable angina, transient ischemic attacks and strokes | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-04 | — | — | US | disclosed |