SCHEMBL7144664

SCHEMBL7144664

Oc1ccc(/C=C/c2ccc(O)c(O)c2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.58
NQO2 P16083 2/20 0.55
LCK P06239 1/20 0.55
NPC1 O15118 2/20 0.53
MTOR P42345 2/20 0.53
APP P05067 7/20 0.50
MAPT P10636 3/20 0.49
NFE2L2 Q16236 2/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA13 Q8N1Q1 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA5B Q9Y2D0 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7144667 1.00 PTPN1 (0.58) PTPN1NQO2LCKNPC1MTOR
Resveratrol SCHEMBL5580566 0.91 TTR (0.66) PTPN1NQO2LCKNPC1MTOR
SCHEMBL574156 0.84 MAOB (0.47) MAPTKDM4EMEN1ALDH1A1LMNA
SCHEMBL30728934 0.83 TRPA1 (0.61) PTPN1MAPTNFE2L2KDM4EMEN1
SCHEMBL21686 0.83 TRPA1 (0.61) PTPN1MAPTNFE2L2KDM4EMEN1
SCHEMBL9742095 0.83 TRPA1 (0.61) PTPN1MAPTNFE2L2KDM4EMEN1
SCHEMBL3671183 0.80 P4HB (0.43) PTPN1MAPTCA12CA2CA3
SCHEMBL3671182 0.80 P4HB (0.43) PTPN1MAPTCA12CA2CA3
SCHEMBL15286224 0.80 RELA (0.73) NQO2NPC1NFE2L2KDM4EALDH1A1
SCHEMBL8965043 0.79 BACE1 (0.70) MAOBABCB1AKR1B1MAOAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6521669-B1 Hydroxystilbene compounds for reducing/inhibiting protein glycation SOCIETE L'OREAL S.A. (FR) 2003-02-18 US claimed