Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.51 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252578 | 0.86 | KDM4E (0.65) | KDM4EHSD17B10HDAC1KEAP1NPC1 | |
| SCHEMBL9744446 | 0.83 | GRIK1 (0.49) | KDM4EGRIK1CLCN2KEAP1NPC1 | |
| SCHEMBL14854686 | 0.83 | SMN1; SMN2 (0.51) | KDM4EHSD17B10HDAC1RAB9ACYP2C19 | |
| SCHEMBL7848417 | 0.82 | PTPN1 (0.56) | GRIK1CLCN2KEAP1NPC1KCNK2 | |
| SCHEMBL3810854 | 0.81 | CLCN2 (0.52) | KDM4EHSD17B10GRIK1CLCN2KEAP1 | |
| SCHEMBL9744178 | 0.81 | KDM4E (0.68) | KDM4EGRIK1CLCN2NPC1RAB9A | |
| SCHEMBL12798622 | 0.81 | GRIK1 (0.51) | KDM4EGRIK1CLCN2KEAP1NPC1 | |
| SCHEMBL13893468 | 0.80 | KDM4E (0.48) | KDM4EHDAC1DYRK1APDPK1NPC1 | |
| SCHEMBL6891543 | 0.80 | KMT2A (0.55) | KDM4EHSD17B10GRIK1CLCN2MEN1 | |
| SCHEMBL5490228 | 0.80 | KDM4E (0.57) | KDM4EHSD17B10GRIK1HDAC1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705287-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226731-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-112707845-B | Preparation method of dacatinib intermediate | 成都伊诺达博医药科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112707845-A | Preparation method of dacomitinib intermediate | 成都伊诺达博医药科技有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-109971210-B | Phenolic azo type reactive dye and preparation method thereof | 南京林业大学 | 2021-04-20 | — | — | CN | disclosed |
| EP-0768301-B1 | N-(2-substituted-3-(2-aminoethyl)-1H-indol-5-yl)-amides as new 5-HT1F agonists | LILLY CO ELI (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6380201-B1 | Methods of treating or ameliorating the symptoms of common cold or allergic rhinitis with serotonin 5-HT1F agonists | ELI LILLY AND COMPANY | 2002-04-30 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6126932-A | INSOLUBLE POLYMER BEARING PENDANT SIDE CHAINS, SAID SIDE CHAINS EACH TERMINATING WITH THE 1-(3-(1-PYRROLIDINYL)-PROPYL)-3-ETHYLCARBODIIMIDE MOIETY. | ELI LILLY AND COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0994109-A2 | 1-(3-(1-Pyrrolidinyl)propyl)-3-ethylcarbodiimide and a solid phase coupling agent | ELI LILLY AND COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0768301-A1 | N-(2-substituted-3-(2-aminoethyl)-1H-indol-5-yl)-amides as new 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5302390-A | ADMINISTERING TO TREAT THROMBOTIC DISEASES | BEECHAM GROUP PLC (GB) | 1994-04-12 | — | — | US | disclosed |
| EP-0297882-B1 | HYBRID PLASMINOGEN ACTIVATORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0297882-A2 | Hybrid plasminogen activators | BEECHAM GROUP PLC (GB) | 1989-01-04 | — | — | EP | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |