SCHEMBL9744178

SCHEMBL9744178

CCC(=O)Nc1cc(F)ccc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.68
ALDH1A1 P00352 4/20 0.68
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
GRIK1 P39086 3/20 0.48
CLCN2 P51788 1/20 0.47
POLB P06746 2/20 0.46
CYP1A2 P05177 1/20 0.46
THRB P10828 1/20 0.46
CYP2C19 P33261 1/20 0.46
HCAR2 Q8TDS4 2/20 0.44
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16854334 0.87 KDM4E (0.55) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL8689054 0.84 GRIK1 (0.48) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL13885544 0.84 ALDH1A1 (0.51) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL7144739 0.81 KDM4E (0.51) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL13018932 0.81 SMN1; SMN2 (0.59) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL12703526 0.81 MEN1 (1.00) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL2608555 0.80 LMNA (0.58) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL13921285 0.80 CLCN2 (0.49) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL9744446 0.79 GRIK1 (0.49) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL27736460 0.78 MEN1 (0.64) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093364-A 5-FLUOROANTHRANILIC FUNGICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-03-03 US disclosed
EP-0360417-A2 Derivatives of 4-fluoroanthranilic acid and their use as fungicides SCHERING AGROCHEMICALS LIMITED (GB) 1990-03-28 EP disclosed