Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227411 | 0.84 | GRIK1 (0.48) | GRIK1CLCN2ACLYKEAP1PYGL | |
| SCHEMBL30227212 | 0.84 | GRIK1 (0.48) | GRIK1CLCN2ACLYKEAP1PYGL | |
| SCHEMBL7144739 | 0.83 | KDM4E (0.51) | GRIK1CLCN2MEN1KMT2AKEAP1 | |
| SCHEMBL7848417 | 0.79 | PTPN1 (0.56) | GRIK1CLCN2KEAP1NPC1 | |
| SCHEMBL3810854 | 0.79 | CLCN2 (0.52) | GRIK1CLCN2HPGDAKR1C3AKR1C2 | |
| SCHEMBL12798622 | 0.79 | GRIK1 (0.51) | GRIK1CLCN2MEN1KMT2AKEAP1 | |
| SCHEMBL9744178 | 0.79 | KDM4E (0.68) | GRIK1CLCN2MEN1KMT2ANPC1 | |
| SCHEMBL2015592 | 0.77 | HTT (0.62) | HPGDHTTPKMMAPTNPC1 | |
| SCHEMBL9743950 | 0.77 | GRIK1 (0.56) | GRIK1CLCN2MEN1KMT2AKEAP1 | |
| SCHEMBL11239532 | 0.76 | ABCB1 (0.57) | HPGDMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |