Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.40 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.40 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743032 | 0.82 | EPHX1 (0.54) | ALDH1A1LMNAEPHX1TSHRMEN1 | |
| SCHEMBL11742553 | 0.72 | TLR9 (0.40) | ALDH1A1LMNAMEN1CYP2C19KMT2A | |
| SCHEMBL2934674 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX1MEN1CYP2C19 | |
| SCHEMBL2934678 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX1MEN1CYP2C19 | |
| SCHEMBL2934676 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAEPHX1MEN1CYP2C19 | |
| SCHEMBL6993376 | 0.70 | P2RY6 (0.41) | ALDH1A1LMNAMEN1KMT2ADNMT3B | |
| SCHEMBL13071712 | 0.69 | SLC5A2 (0.47) | ALDH1A1 | |
| SCHEMBL10484170 | 0.67 | KCNA4 (0.41) | KCNA4KCNA1KCNAB1ALDH1A1LMNA | |
| SCHEMBL9100356 | 0.67 | TDP1 (0.43) | ALDH1A1KDM1AMEN1KMT2ADNMT3B | |
| SCHEMBL10484173 | 0.67 | KCNA4 (0.41) | KCNA4KCNA1KCNAB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287155-A1 | ENZYMATIC CONVERSION OF EPOXIDES | Rijksuniversiteit Groningen (NL) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001090397-A1 | ENZYMATIC CONVERSION OF EPOXIDES | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2001-11-29 | — | — | WO | disclosed |
| CN-1282243-A | Pharmaceutical composition containing anilide derivative for antagonizing CCR5 | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| WO-2000037619-A2 | MUTANT EPOXIDE HYDROLASES | DSM N.V. (NL) | 2000-06-29 | — | — | WO | disclosed |
| EP-1013768-A1 | Mutant epoxide hydrolases | DSM N.V. (NL) | 2000-06-28 | — | — | EP | disclosed |