Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136149 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7511016 | 0.86 | CSNK2A1 (0.30) | CSNK2A1 | |
| SCHEMBL7137678 | 0.86 | SCN9A (0.36) | SCN9A | |
| SCHEMBL7139134 | 0.82 | EPHX1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7510453 | 0.81 | KDM4E (0.31) | — | |
| SCHEMBL7143023 | 0.79 | P2RX7 (0.32) | CSNK2A1 | |
| SCHEMBL7144422 | 0.78 | SIGMAR1 (0.31) | CSNK2A1 | |
| Hydrochloric Acid SCHEMBL7517090 | 0.77 | OPRK1 (0.32) | CSNK2A1 | |
| SCHEMBL7144492 | 0.74 | MEN1 (0.39) | SCN9A | |
| SCHEMBL2639483 | 0.73 | SCN9A (0.38) | SCN9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | claimed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | claimed |
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |