Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.60 |
| ▸ | LTA4H | P09960 | 5/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979678 | 0.84 | LTA4H (0.63) | ACELTA4HACE2 | |
| SCHEMBL6973372 | 0.84 | LTA4H (0.63) | ACELTA4HACE2 | |
| SCHEMBL6979674 | 0.84 | LTA4H (0.63) | ACELTA4HACE2 | |
| SCHEMBL6975531 | 0.83 | LTA4H (0.64) | ACELTA4HACE2 | |
| SCHEMBL6442125 | 0.82 | ACE (0.74) | ACELTA4HACE2 | |
| SCHEMBL6442128 | 0.82 | ACE (0.74) | ACELTA4HACE2 | |
| SCHEMBL2881573 | 0.82 | MEN1 (0.59) | ACELTA4HACE2 | |
| SCHEMBL28255253 | 0.82 | ACE (0.63) | ACELTA4HACE2 | |
| SCHEMBL28255251 | 0.82 | ACE (0.63) | ACELTA4HACE2 | |
| SCHEMBL8655052 | 0.81 | LTA4H (0.59) | ACELTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642253-B2 | Thrombin inhibitors comprising an aminoisoquinoline group | AKZO NOBEL N. V. (NL) | 2003-11-04 | — | — | US | disclosed |
| US-20030166579-A1 | THROMBIN INHIBITORS COMPRISING AN AMINOISOQUINOLINE GROUP | N.V. ORGANON (NL) | 2003-09-04 | — | — | US | disclosed |
| WO-2002004423-A9 | THROMBIN INHIBITORS COMPRISING AN AMINOISOQUINOLINE GROUP | AKZO NOBEL NV (NL) | 2003-05-15 | — | — | WO | disclosed |
| EP-1303491-A1 | THROMBIN INHIBITORS COMPRISING AN AMINOISOQUINOLINE GROUP | Akzo Nobel N.V. (NL) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002004423-A1 | THROMBIN INHIBITORS COMPRISING AN AMINOISOQUINOLINE GROUP | AKZO NOBEL N.V. (NL) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166579-A1 | THROMBIN INHIBITORS COMPRISING AN AMINOISOQUINOLINE GROUP | F2, TFPI, SERPINC1 | ACE 79/4885LTA4H 853/4885ACE2 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.