Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 15/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 13/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037793 | 0.90 | ENPP3 (0.39) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL7141882 | 0.87 | ENPP3 (0.36) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL5035960 | 0.84 | ENPP3 (0.39) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL5040705 | 0.84 | ENPP3 (0.36) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL5036486 | 0.83 | ENPP3 (0.38) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL7145635 | 0.82 | ENPP3 (0.35) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL6017758 | 0.81 | ABL1 (0.39) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL7147110 | 0.81 | MEN1 (0.36) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL7142590 | 0.81 | HTR6 (0.37) | ENPP3ENPP1ENPP2MAPTHTT | |
| SCHEMBL7163606 | 0.80 | ENPP3 (0.35) | ENPP3ENPP1ENPP2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298125-A1 | Substituted benzimidazole compounds and their use for the treatment of cancer | Aventis Pharma S.A. (FR) | 2003-04-02 | — | — | EP | disclosed |