Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714449 | 0.80 | PDGFRB (0.53) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL21295700 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PDGFRBPDGFRANPC1POLB | |
| SCHEMBL716130 | 0.76 | PIK3CA (0.37) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL5303005 | 0.75 | CYP2A6 (0.51) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL714577 | 0.75 | PDGFRB (0.42) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL28135503 | 0.74 | NPC1 (0.62) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL713492 | 0.74 | CCR1 (0.50) | CYP2A6ALDH1A1NPC1POLBRAB9A | |
| SCHEMBL13370752 | 0.72 | TGFBR1 (0.43) | ALDH1A1NPC1POLBRAB9ABCHE | |
| SCHEMBL18627394 | 0.72 | NPC1 (0.53) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 | |
| SCHEMBL4367935 | 0.71 | CYP2A6 (0.41) | CYP2A6ALDH1A1PDGFRBPDGFRANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
| EP-2299825-A1 | INHIBITORS OF AKT ACTIVITY | Merck Sharp & Dohme Corp. (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009148887-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2009-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | CYP2A6 3399/4885ALDH1A1 1391/4885PDGFRB 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.