Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837934 | 0.91 | HTT (0.46) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6836624 | 0.83 | ALDH1A1 (0.45) | HTTLMNAL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL6837509 | 0.80 | HTT (0.51) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6944130 | 0.80 | NPC1 (0.42) | SMN1; SMN2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6836434 | 0.79 | L3MBTL1 (0.40) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6837883 | 0.79 | SMN1; SMN2 (0.52) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6837620 | 0.79 | SMN1; SMN2 (0.53) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6837691 | 0.79 | HTT (0.53) | HTTLMNAL3MBTL1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7141614 | 0.79 | RXFP1 (0.51) | HTTLMNASMN1; SMN2POLBHSD17B10 | |
| SCHEMBL6837936 | 0.78 | SMN1; SMN2 (0.49) | HTTLMNAL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |