⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662150 | 0.76 | — | — | |
| SCHEMBL4463578 | 0.71 | — | — | |
| SCHEMBL981138 | 0.71 | — | — | |
| SCHEMBL5072580 | 0.71 | — | — | |
| SCHEMBL9846945 | 0.71 | — | — | |
| SCHEMBL983305 | 0.67 | — | — | |
| SCHEMBL10613039 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL24625081 | 0.67 | SORT1 (0.33) | — | |
| SCHEMBL6535942 | 0.67 | — | — | |
| SCHEMBL364755 | 0.65 | GPR84 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090231-B1 | PROCESS FOR THE PREPARATION OF 3-ALKYL-2,5-DIHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | claimed |
| EP-1138679-B1 | HYDRONAPHTHO 2,3-c]FURAN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAGAMI CHEM RES (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6392059-B1 | THERAPY FOR ALZHEIMER'S DISEASE | SAGAMI CHEMICAL REASEARCH CENTER (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-1138679-A1 | HYDRONAPHTHO 2,3-c]FURAN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-4650896-A | Preparation of 2-alkyl-4,4-diacyloxybut-2-enals | BASF AKTIENGESELLSCHAFT (DE) | 1987-03-17 | — | — | US | disclosed |
| EP-0162384-B1 | PROCESS FOR THE PREPARATION OF 2-ALKYL-4,4-DIACYLOXY-2-BUTENALS | BASF Aktiengesellschaft (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0162384-A1 | Process for the preparation of 2-alkyl-4,4-diacyloxy-2-butenals | BASF Aktiengesellschaft (DE) | 1985-11-27 | — | — | EP | disclosed |
| EP-0090231-B1 | PROCESS FOR THE PREPARATION OF 3-ALKYL-2,5-DIHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | disclosed |
| EP-0090231-B1 | PROCESS FOR THE PREPARATION OF 3-ALKYL-2,5-DIHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | disclosed |
| US-4521342-A | Preparation of 2-alkyl-4,4-diacyloxybut-2-enals | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-04 | — | — | US | disclosed |
| EP-0089585-B1 | PROCESS FOR THE PREPARATION OF 2-ALKYL-4,4-DIACYLOXY-2-BUTENALS | BASF Aktiengesellschaft (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0090231-A1 | Process for the preparation of 3-alkyl-2,5-dihydrofuran-2-ones | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0090231-A1 | Process for the preparation of 3-alkyl-2,5-dihydrofuran-2-ones | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0090231-A1 | Process for the preparation of 3-alkyl-2,5-dihydrofuran-2-ones | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0089585-A1 | Process for the preparation of 2-alkyl-4,4-diacyloxy-2-butenals | BASF Aktiengesellschaft (DE) | 1983-09-28 | — | — | EP | disclosed |