Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037428 | 0.77 | AAK1 (0.35) | — | |
| SCHEMBL7032706 | 0.71 | CTSK (0.36) | — | |
| SCHEMBL6986613 | 0.64 | EPHX1 (0.33) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5927975 | 0.63 | EPHX1 (0.61) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14895043 | 0.63 | EPHX1 (0.42) | EPHX1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6212781 | 0.63 | CTSK (0.33) | EPHX1ALDH1A1TSHR | |
| SCHEMBL7039308 | 0.63 | METAP2 (0.33) | — | |
| SCHEMBL7037265 | 0.62 | METAP2 (0.34) | ALDH1A1 | |
| SCHEMBL5927952 | 0.62 | EPHX1 (0.65) | EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5927948 | 0.62 | EPHX1 (0.65) | EPHX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345931-A2 | CYSTEINE PROTEASE INHIBITORS | Medivir UK Ltd (GB) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002040462-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2002-05-23 | — | — | WO | disclosed |