Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504790 | 0.89 | SLC13A5 (0.54) | SLC13A5PPARGPPARAMEN1KMT2A | |
| SCHEMBL4207640 | 0.87 | SLC13A5 (0.60) | SLC13A5PPARGPPARAMEN1KMT2A | |
| SCHEMBL26659934 | 0.81 | FYN (0.56) | SLC13A5PPARGPPARAMMEMMEL1 | |
| Hydrogen Sulfide SCHEMBL27792272 | 0.80 | LMNA (0.55) | PPARGPPARAMEN1KMT2AALDH1A1 | |
| SCHEMBL3677264 | 0.78 | FFAR1 (0.66) | SLC13A5PPARGPPARAMMEMMEL1 | |
| SCHEMBL12189290 | 0.78 | L3MBTL1 (0.60) | SLC13A5PPARGPPARAALDH1A1TDP1 | |
| SCHEMBL14319105 | 0.78 | PPARG (0.48) | PPARGPPARAMEN1KMT2AMME | |
| SCHEMBL9417743 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL5213839 | 0.78 | PPARG (0.63) | PPARGPPARAMMEMMEL1ITGA4 | |
| SCHEMBL31398354 | 0.78 | PPARG (0.63) | PPARGPPARAMMEMMEL1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030143701-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-31 | — | — | US | disclosed |
| EP-0924194-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6528686-B1 | Reacting primary amine and ketone functionalized derivatives; catalytically reducing | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0939134-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0654534-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0939134-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0924193-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5629200-A | MICROORGANISM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0654534-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0400011-B1 | NEW PHENYLETHANOLAMINES | BOEHRINGER INGELHEIM VETMED (DE) | 1994-01-26 | — | — | EP | disclosed |
| US-5232946-A | Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency | DR. KARL THOMAE GMBH (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0400011-A1 | NEW PHENYLETHANOLAMINES. | BOEHRINGER INGELHEIM VETMED (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0375791-A1 | Phenyl ethanol amines, their use as pharmaceutical compounds and as performance stimulants in animals, as well as processes for their preparation | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1990-07-04 | — | — | EP | disclosed |
| WO-1990006299-A1 | NEW PHENYLETHANOLAMINES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1990-06-14 | — | — | WO | disclosed |