Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154078 | 0.82 | RAB9A (0.61) | MAOBMAOANOS1NOS2MAPT | |
| SCHEMBL7149299 | 0.81 | NOS1 (0.57) | MAOBMAOANOS1NOS2MAPT | |
| SCHEMBL14611349 | 0.81 | MAOB (0.60) | MAOBMAOANOS1NOS2SGMS2 | |
| SCHEMBL6078442 | 0.81 | NOS1 (0.60) | MAOBNOS1NOS2MAPTRAB9A | |
| SCHEMBL11959694 | 0.80 | MAOB (0.72) | MAOBMAOANR4A2PARP10 | |
| SCHEMBL1323646 | 0.80 | RAB9A (0.62) | NOS1NOS2MAPTRAB9ANPSR1 | |
| SCHEMBL30150593 | 0.80 | RAB9A (0.62) | NOS1NOS2MAPTRAB9ANPSR1 | |
| SCHEMBL6119008 | 0.79 | MAOB (0.68) | MAOBMAOANR4A2PARP10 | |
| Bromide SCHEMBL27462942 | 0.78 | RAB9A (0.60) | NOS1NOS2MAPTRAB9ANPSR1 | |
| SCHEMBL28011530 | 0.78 | MAPK1 (0.64) | MAOBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667327-B2 | Pyridine amido derivatives | HOFFMANN-LA ROCHE INC. | 2003-12-23 | — | — | US | disclosed |