Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 4/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972310 | 0.86 | TRPV3 (0.39) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL8209225 | 0.82 | IKBKE (0.36) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL31342020 | 0.82 | NPC1 (0.36) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL15729348 | 0.80 | QDPR (0.50) | QDPRESR2ESR1ACMSD | |
| SCHEMBL30746608 | 0.80 | QDPR (0.50) | QDPRESR2ESR1ACMSD | |
| SCHEMBL31063246 | 0.79 | QDPR (0.43) | QDPRESR2ESR1ACMSDKIF11 | |
| SCHEMBL1506454 | 0.79 | SLC6A2 (0.47) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL30832447 | 0.79 | HTR2A (0.39) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL1809044 | 0.78 | TRPV3 (0.35) | IKBKETBK1TRPV3NPC1RAB9A | |
| SCHEMBL14403053 | 0.78 | ESR2 (0.42) | IKBKETBK1TRPV3ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983225-B1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| US-6395351-B1 | MIXTURE; OPTICS | ROLIC AG (CH) | 2002-05-28 | — | — | US | disclosed |
| EP-0983225-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | Rolic AG (CH) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052905-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 1998-11-26 | — | — | WO | disclosed |