Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 5/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15729348 | 1.00 | QDPR (0.50) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL7149585 | 0.92 | ESR2 (0.55) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL7149586 | 0.92 | ESR2 (0.55) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL10021047 | 0.92 | ACMSD (0.51) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL21237804 | 0.91 | ESR2 (0.56) | QDPRACMSDESR2WDR5ESR1 | |
| SCHEMBL30215678 | 0.90 | ACMSD (0.57) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL21630424 | 0.90 | ACMSD (0.57) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL13072706 | 0.90 | ACMSD (0.57) | QDPRACMSDESR2HDAC4HDAC2 | |
| SCHEMBL21527334 | 0.87 | QDPR (0.71) | QDPRACMSDESR2 | |
| SCHEMBL31063246 | 0.87 | QDPR (0.43) | QDPRACMSDESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |