Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105847 | 0.90 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| 1,2-Dimethoxybenzene SCHEMBL27631200 | 0.88 | CA1 (0.59) | ABCB1MEN1KMT2ATTRALDH1A1 | |
| SCHEMBL467588 | 0.88 | IDO1 (0.55) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL15049434 | 0.88 | IDO1 (0.55) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| Acetone SCHEMBL27450214 | 0.81 | MTNR1A (0.56) | IDO1TAAR1MEN1KMT2ANPC1 | |
| (Chloromethyl)Benzene SCHEMBL28872193 | 0.81 | ABCB1 (0.50) | ABCB1NPC1RAB9ATTRALDH1A1 | |
| SCHEMBL6299863 | 0.79 | HSP90AA1 (0.50) | ABCB1MEN1KMT2AKCNH2NPC1 | |
| (Chloromethyl)Benzene SCHEMBL27327539 | 0.79 | TP53 (0.46) | IDO1TTRALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL621779 | 0.78 | HTR1A (0.58) | ABCB1IDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL8964423 | 0.76 | BCHE (0.68) | MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971901-B1 | PHTHALAZINONES | ALTANA PHARMA AG (DE) | 2003-02-26 | — | — | EP | disclosed |