Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749366 | 0.76 | KDM4E (0.54) | ICAM1 | |
| SCHEMBL8388202 | 0.55 | CA2 (0.48) | ALDH1A1TDP1FBP1 | |
| SCHEMBL344618 | 0.55 | SMN1; SMN2 (0.52) | ALDH1A1TDP1 | |
| SCHEMBL29640421 | 0.54 | NOX1 (0.43) | ALDH1A1TDP1ICAM1 | |
| SCHEMBL3399311 | 0.53 | SMN1; SMN2 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL27552157 | 0.53 | PGK1 (0.49) | ALDH1A1FBP1 | |
| SCHEMBL23000023 | 0.52 | CA2 (0.44) | ALDH1A1TDP1FBP1 | |
| SCHEMBL2171752 | 0.52 | CA2 (0.71) | ALDH1A1TDP1 | |
| SCHEMBL14549173 | 0.51 | ALDH1A1 (1.00) | ALDH1A1TDP1 | |
| SCHEMBL11799279 | 0.51 | TYR (0.59) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |