Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144169 | 0.84 | KIF11 (0.50) | KIF11KCNH2MEN1KMT2A | |
| SCHEMBL7147416 | 0.84 | KIF11 (0.50) | KIF11KCNH2MEN1KMT2A | |
| SCHEMBL19652449 | 0.84 | KIF11 (0.58) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL2898260 | 0.84 | KIF11 (0.60) | KIF11KCNH2MEN1KMT2A | |
| SCHEMBL2686112 | 0.81 | KIF11 (0.64) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8592606 | 0.80 | KIF11 (0.60) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL5838167 | 0.80 | KIF11 (0.60) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7541631 | 0.80 | KIF11 (0.68) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL3905396 | 0.78 | KIF11 (0.50) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL3902937 | 0.78 | KIF11 (0.50) | KIF11KCNH2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030143607-A1 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | YANG GUOHAN (US) | 2003-07-31 | — | — | US | disclosed |
| US-6504019-B2 | Used in place of conventionally labeled oligonucleotides for a variety of hybridization reactions | BAYER CORPORATION | 2003-01-07 | — | — | US | disclosed |
| US-20020015953-A1 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | BAYER CORPORATION | 2002-02-07 | — | — | US | disclosed |
| EP-1136569-A2 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | Bayer Corporation (US) | 2001-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020015953-A1 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | DNTT, NSUN3, NCL | KIF11 1721/4885KCNH2 2412/4885LMNA 475/4885 |
| US-20030143607-A1 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | DNTT, NSUN3, NCL | KIF11 1721/4885KCNH2 2412/4885LMNA 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.