Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147740 | 0.81 | KIF11 (0.61) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL26068376 | 0.79 | KIF11 (0.61) | KIF11KCNH2 | |
| SCHEMBL2897015 | 0.79 | KIF11 (0.61) | KIF11KCNH2 | |
| SCHEMBL1263156 | 0.79 | KIF11 (0.61) | KIF11KCNH2 | |
| SCHEMBL7912698 | 0.79 | KIF11 (0.45) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL19652449 | 0.79 | KIF11 (0.58) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL5838167 | 0.79 | KIF11 (0.60) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8592606 | 0.79 | KIF11 (0.60) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL14432808 | 0.78 | KIF11 (1.00) | KIF11 | |
| SCHEMBL14537457 | 0.78 | KIF11 (1.00) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9435796-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-8436153-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120115133-A1 | CYANINE DYES | BIOSEARCH TECHNOLOGIES INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-20100136567-A1 | CYANINE DYES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7705150-B2 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20050214833-A1 | Cyanine dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2005-09-29 | — | — | US | disclosed |
| US-6187913-B1 | Covalently crosslinked oligonucleotides, preparation method and synthon which is of use in the method | GENSET (FR) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136567-A1 | CYANINE DYES | ACR, IK, TYR | KIF11 827/4885KCNH2 1766/4885LMNA 2300/4885 |
| US-20050214833-A1 | Cyanine dyes | ACR, IK, TYR | KIF11 827/4885KCNH2 1766/4885LMNA 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.