Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902937 | 0.90 | KIF11 (0.50) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7147740 | 0.78 | KIF11 (0.61) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL19652449 | 0.74 | KIF11 (0.58) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL6039133 | 0.74 | KIF11 (0.46) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL2898260 | 0.73 | KIF11 (0.60) | KIF11KCNH2KMT2AMEN1 | |
| SCHEMBL14937220 | 0.73 | KIF11 (0.46) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8399786 | 0.72 | KIF11 (0.43) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL3496480 | 0.71 | KIF11 (0.54) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL27757625 | 0.71 | KIF11 (0.52) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL2686112 | 0.71 | KIF11 (0.64) | KIF11KCNH2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626952-B1 | MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS | FRIZ BIOCHEM GES FÜR BIOANALYTIK MBH (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-7601848-B2 | Multifunctional reagent for the synthesis of thiol modified oligomers | FIDICULA GMBH (DE) | 2009-10-13 | — | — | US | disclosed |
| US-20050153291-A1 | Multifunctional reagent for the synthesis of thiol modified oligomers | FRIZ BIOCHEM GESELLSCHAFT FUR BIOANALYTIK MBH (DE) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153291-A1 | Multifunctional reagent for the synthesis of thiol modified oligomers | CBR3, NOX3, CBR1 | KIF11 3893/4885KCNH2 623/4885LMNA 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.