Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813489 | 0.98 | GRIK1 (0.48) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL5968482 | 0.91 | DPP7 (0.50) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL29565162 | 0.83 | GRIK1 (0.55) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL8425258 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL28888696 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL14038058 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL2920941 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL18151772 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL6762998 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 | |
| SCHEMBL27539628 | 0.83 | GRIK1 (0.53) | GRIK1GRIK2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448394-B1 | FORMATION OF BLOCKED ISOCYANTES WITHOUT FREE ISOCYANATE PRESENT BY REACTING AMINE WITH CARBONIC ACID DERIVATIVE | DSM N.V. (NL) | 2002-09-10 | — | — | US | claimed |
| US-20030088020-A1 | Powder paint binder composition | DSM N.V. (NL) | 2003-05-08 | — | — | US | disclosed |
| EP-1263829-A1 | POWDER PAINT BINDER COMPOSITION | DSM N.V. (NL) | 2002-12-11 | — | — | EP | disclosed |
| US-6448394-B1 | FORMATION OF BLOCKED ISOCYANTES WITHOUT FREE ISOCYANATE PRESENT BY REACTING AMINE WITH CARBONIC ACID DERIVATIVE | DSM N.V. (NL) | 2002-09-10 | — | — | US | disclosed |
| US-20020028932-A1 | Process for the preparation of an N-alkyl or N-aryl carbamoyl derivative | DSM IP ASSETS B.V. (NL) | 2002-03-07 | — | — | US | disclosed |
| WO-2001064769-A1 | POWDER PAINT BINDER COMPOSITION | DSM N.V. (NL) | 2001-09-07 | — | — | WO | disclosed |
| EP-1130039-A1 | Powder paint binder composition | DSM N.V. (NL) | 2001-09-05 | — | — | EP | disclosed |
| EP-1115709-A1 | PROCESS FOR THE PREPARATION OF AN N-ALKYL OR N-ARYL CARBAMOYL DERIVATIVE | DSM N.V. (NL) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017169-A1 | PROCESS FOR THE PREPARATION OF AN N-ALKYL OR N-ARYL CARBAMOYL DERIVATIVE | DSM N.V. (NL) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028932-A1 | Process for the preparation of an N-alkyl or N-aryl carbamoyl derivative | OGDH, DOHH, CFH | GRIK1 2140/4885GRIK2 3015/4885GNAI3 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.