SCHEMBL7148219

SCHEMBL7148219

c1ccc(CN(Cc2ccccc2)c2ccccc2N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
ALDH1A1 P00352 2/20 0.52
CYP2C19 P33261 2/20 0.52
AOC3 Q16853 1/20 0.48
NR3C1 P04150 9/20 0.47
PGR P06401 1/20 0.47
NR3C2 P08235 1/20 0.47
AR P10275 1/20 0.47
MGLL Q99685 2/20 0.46
CNR2 P34972 1/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
PKM P14618 1/20 0.43
ALOX12 P18054 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2676900 0.84 KDM4E (0.46) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL11523001 0.84 TSHR (0.45) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL2586556 0.84 NR3C1 (0.46) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL3006766 0.84 TRPM8 (0.54) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL9490739 0.84 TSHR (0.45) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL7651498 0.84 TSHR (0.45) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL28842673 0.84 TSHR (0.45) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL29013279 0.84 NR3C1 (0.46) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL22118149 0.84 TSHR (0.47) TSHRALDH1A1CYP2C19AOC3NR3C1
SCHEMBL1704796 0.82 PTPN1 (0.45) TSHRALDH1A1CYP2C19AOC3NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US claimed
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US disclosed