Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148219 | 0.84 | TSHR (0.54) | TSHRMGLLCYP2C19ALDH1A1NR3C1 | |
| SCHEMBL1803882 | 0.82 | NR1H2 (0.50) | TSHRALDH1A1NR1H2NR1H3 | |
| SCHEMBL11509877 | 0.81 | TSHR (0.46) | TSHRMGLLCYP2C19ALDH1A1CA2 | |
| SCHEMBL9861882 | 0.80 | ALOX5 (0.46) | TSHRMGLLCYP2C19ALDH1A1BCL2 | |
| SCHEMBL10620283 | 0.80 | CNR2 (0.46) | TSHRCA2NR1H2NR1H3 | |
| SCHEMBL1926093 | 0.78 | TSHR (0.51) | TSHRALDH1A1 | |
| SCHEMBL10873099 | 0.77 | CYP2C19 (0.53) | TSHRCYP2C19ALDH1A1NR3C1PGR | |
| SCHEMBL6553755 | 0.75 | TSHR (0.39) | TSHRMGLLCYP2C19ALDH1A1NR3C1 | |
| SCHEMBL20506819 | 0.74 | CA1 (0.51) | TSHRCA2 | |
| SCHEMBL7651498 | 0.74 | TSHR (0.45) | TSHRMGLLCYP2C19ALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898842-A1 | MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS | Life Technologies Corporation (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132487-A1 | MODIFIED RHODAMINE DYE AND USE THEREOF IN BIOLOGICAL ASSAYS | Life Technologies Corporation (US) | 2020-06-25 | — | — | WO | disclosed |