Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19678704 | 0.95 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL343331 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL308882 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL29632227 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL29632107 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL7100581 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL30833194 | 0.89 | MAPT (0.53) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL28062236 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL8846476 | 0.86 | MAPT (0.44) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL240794 | 0.85 | GABRP (0.59) | ALDH1A1MAPTKDM4ECYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620864-B2 | With a plasticizer, a catalyst for hardening by ring opening, a catalyst for hardening by light and as accelerator a p-aminobenzoic acid alkyl ester, N,N-disubstituted by hydroxyalkyl groups; free of contraction and adhesiveness | LSP DENTAL CHEMISTRY AG (CH) | 2003-09-16 | — | — | US | disclosed |
| US-20020040103-A1 | Epoxy compounds for use in dental medicine and/or dentistry | LSP DENTAL CHEMISTRY AG (CH) | 2002-04-04 | — | — | US | disclosed |