SCHEMBL71486

SCHEMBL71486

O=C(O)c1oc(C(=O)O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.46
LMNA P02545 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NR4A2 P43354 1/20 0.41
PDGFRA P16234 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK5 Q00535 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HNF4A P41235 1/20 0.41
DAO P14920 1/20 0.40
TSHR P16473 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978711 0.87 PTPN1 (0.49) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL3977576 0.87 PTPN1 (0.41) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL28130850 0.86 PTPN1 (0.47) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL3973139 0.86 PTPN1 (0.40) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL3976143 0.81 PDE4A (0.41) PTPN1LMNAALDH1A1HPGDPDGFRA
SCHEMBL1713043 0.81 PTPN22 (0.43) PTPN1CYP1A2ALDH1A1HPGDNPC1
SCHEMBL5963637 0.80 NPC1 (0.40) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL3610930 0.80 PTPN1 (0.59) PTPN1LMNAMAPTHTTALDH1A1
SCHEMBL3361896 0.78 ALDH1A1 (0.61) LMNAHTTALDH1A1HPGDKDM4E
SCHEMBL72038 0.77 PTGS1 (0.54) LMNAHTTALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994546-A Bio-based copolyester and preparation method thereof 合肥利夫生物科技有限公司 2024-11-22 CN disclosed
CN-118994547-A 2, 5-Furandicarboxylic acid based copolyester and synthesis method thereof 合肥利夫生物科技有限公司 2024-11-22 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PTPN1 3997/4885LMNA 2207/4885CYP1A2 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.