SCHEMBL72038

SCHEMBL72038

COC(=O)c1oc(C(=O)OC)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.54
LMNA P02545 2/20 0.51
TSHR P16473 1/20 0.50
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
RAB9A P51151 1/20 0.46
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CELA1 Q9UNI1 1/20 0.45
TP53 P04637 1/20 0.44
AR P10275 1/20 0.44
FGFR1 P11362 1/20 0.44
SRC P12931 1/20 0.44
FGFR2 P21802 1/20 0.44
FGFR4 P22455 1/20 0.44
FGFR3 P22607 1/20 0.44
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975977 0.90 PTGS1 (0.49) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL3974214 0.88 PTGS1 (0.48) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL3978064 0.88 PTGS1 (0.48) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL27448744 0.82 PTGS1 (0.46) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL22349646 0.80 KDM4E (0.58) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL3977063 0.78 LMNA (0.45) PTGS1LMNATSHRALDH1A1SMN1; SMN2
SCHEMBL71486 0.77 PTPN1 (0.46) LMNATSHRKDM4EALDH1A1RAB9A
SCHEMBL11227892 0.76 LMNA (0.64) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL9825659 0.75 PTGS1 (0.48) PTGS1LMNATSHRKDM4EALDH1A1
SCHEMBL3977117 0.74 ALDH1A1 (0.48) PTGS1LMNATSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PTGS1 2544/4885LMNA 2207/4885TSHR 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.